Injury Report:
Lions injury designations:
| POS. | PLAYER | INJURY | STATUS |
| RB | Joique Bell | Ankle | Out |
| TE | Eric Ebron | Knee | Out |
| DT | Haloti Ngata | Calf | Out |
| DE | Ziggy Ansah | Shoulder | Probable |
| OLB | DeAndre Levy | Hip | Probable |
| OLB | Travis Lewis | Ankle | Probable |
| CB | Rashean Mathis | Calf | Probable |
| WR | Lance Moore | Ankle | Probable |
| OT | Corey Robinson | Ankle | Probable |
| P | Sam Martin | Left Knee | Probable |
| TE | Brandon Pettigrew | Hamstring | Probable |
| CB | Darius Slay | Quadricep | Probable |
| SS | James Ihedigbo | Quadricep | Questionable |
| OG | Larry Warford | Ankle | Questionable |
Cardinals injury designations:
| POS. | PLAYER | INJURY | STATUS |
| S | Chris Clemons | Hamstring | Probable |
| RB | Andre Ellington | Knee | Probable |
| LB | Alani Fua | Hamstring | Probable |
| S | Rashad Johnson | Hip | Probable |
| DT | Frostee Rucker | Thigh | Probable |
| OLB | LaMarr Woodley | Thigh | Probable |
| CB | Justin Bethel | Foot | Probable |
| TE | Darren Fells | Hip | Questionable |
| WR | J.J. Nelson | Shoulder | Questionable |