Round 4:
| Pick | Pk. | Team | Player | Position | School |
| 101 | 1 | Green Bay Packers | Simmie Cobbs Jr. | WR | Indiana |
| 102 | 2 | Tampa Bay Buccaneers | Joseph Noteboom | OT | TCU |
| 103 | 3 | Houston Texans | Kalen Ballage | RB | Arizona State |
| 104 | 4 | Indianapolis Colts | Shaquem Griffin | LB | UCF |
| 105 | 5 | Chicago Bears | Uchenna Nwosu | LB | USC |
| 106 | 6 | Denver Broncos | Holton Hill | CB | Texas |
| 107 | 7 | New York Jets | Deon Cain | WR | Clemson |
| 108 | 8 | New York Giants | Cole Madison | OL | Washington State |
| 109 | 9 | Washington Redskins | Keke Coutee | WR | Texas Tech |
| 110 | 10 | Oakland Raiders | Durham Smythe | TE | Notre Dame |
| 111 | 11 | Los Angeles Rams | Duke Eijofor | RUSH | Wake Forest |
| 112 | 12 | Cincinnati Bengals | Jalyn Holmes | DE | Ohio State |
| 113 | 13 | Denver Broncos | Dorian O’Daniel | LB | Clemson |
| 114 | 14 | Cleveland Browns | Chukwuma Okrafor | OT | Western Michigan |
| 115 | 15 | Chicago Bears | Derrick Nnadi | DT | Florida State |
| 116 | 16 | Dallas Cowboys | Marcell Ateman | WR | Oklahoma State |
| 117 | 17 | Detroit Lions | Tim Settle | DT | Virginia Tech |
| 118 | 18 | Baltimore Ravens | Scott Quessenberry | OL | UCLA |
| 119 | 19 | Los Angeles Chargers | Josh Adams | RB | Notre Dame |
| 120 | 20 | Seattle Seahawks | Tyquan Lewis | DE | Ohio State |
| 121 | 21 | Buffalo Bills | Jeff Holland | LB | Auburn |
| 122 | 22 | Kansas City Chiefs | Kevin Toliver II | CB | LSU |
| 123 | 23 | Miami Dolphins | Tony Brown | CB | Alabama |
| 124 | 24 | Kansas City Chiefs | Christopher Herndon | TE | Miami |
| 125 | 25 | Tennessee Titans | Oren Burks | LB | Vanderbilt |
| 126 | 26 | Atlanta Falcons | Sean Welsh | OG | Iowa |
| 127 | 27 | New Orleans Saints | Chase Litton | QB | Marshall |
| 128 | 28 | San Francisco 49ers | Bo Scarbrough | RB | Alabama |
| 129 | 29 | Jacksonville Jaguars | DaShawn Hand | DE | Alabama |
| 130 | 30 | Philadelphia Eagles | Justin Jackson | RB | Northwestern |
| 131 | 31 | Miami Dolphins | Geron Christian | OT | Louisville |
| 132 | 32 | Philadelphia Eagles | Jamarco Jones | OT | Ohio State |
| 133 | 33 | Green Bay Packers | Alex Cappa | OT | Humbolt State |
| 134 | 34 | Arizona Cardinals | Quenton Meeks | CB | Stanford |
| 135 | 35 | Los Angeles Rams | Hercules Mataafa | DE | Washington State |
| 136 | 36 | Los Angeles Rams | Ade Aruna | RUSH | Tulane |
| 137 | 37 | Dallas Cowboys | Jordan Whitehead | S | Pittsburgh |
Up Next: Round 5
